Bacopa Monnieri


Background


Bacopa Monnieri | Brother Nature NootropicsBacopa Monnieri is a perennial herb that grows naturally in the wetlands of many tropical and subtropical regions of the world. [1] Commonly referred to as Brahmi in Ayurvedic medicine, this herb has is believed to prevent aging, re-establish youth, prevent disease, promote healthy longevity, and strengthen life. In fact, when translated from Sanskrit, the word Brahmi means "expands consciousness" and is named after Brahma, the creator of the Hindu pantheon. Bacopa Monnieri is most commonly known for and studied as a cognitive enhancer, but the leaves of the plant have been used for centuries in paste form to treat burns, rashes, and even arthritis! [2]

 

Bacopa and Your Brain

Most of the recent clinical studies on bacopa have investigated its effect on cognition, memory, anxiety, and even depression in healthy volunteers or in Alzheimer’s patients. In one 2011 open-label, prospective, uncontrolled, non-randomized study, 39 Alzheimer’s patients (60-65 years) were given 300 mg of Bacognize® (alcohol extract standardized by HPLC for 10-20% bacopa glycosides; Verdure Sciences, Noblesville, Indiana) twice daily for 6 months. Patients showed significant improvements in various areas, including attention, orientation of person, place, and time, and in reading, writing, and comprehension.

Clinical research of Bacopa as a mechanism for memory enhancement is still in early stages, however there have been several high quality, randomized, double-blind, placebo-controlled studies of the effects of the herb on the cognition of healthy adults. One such study conducted a systematic review resulting in evidence that Bacopa could potentially be clinically prescribed as a memory enhancer. [3]

Another study compared the nootropic effects of Bacon Monnieri to Panax Ginseng and Modafinil (a synthetic wakefulness drug commonly used as a nootropic). It was found that taking constant supplementation of Bacopa produced the most consistent and largest effects of the three. [4] The largest effect sizes for Bacopa were evident for verbal learning tasks such as delayed word and word pair recall, while moderate effect sizes were seen for attention and information processing tasks. Evidence from this study does a lot to prove the potency of Bacopa, particularly in the space of verbal recall.

Two additional human trials of a combined 122 healthy adults found significantly improved speed of visual information processing, learning rate, memory consolidation, and state anxiety compared to placebo. [5] [6] The subjects were given 300mg of Bacopa (with at least 55% Bacosides) daily for 12 weeks. Researchers found Bacopa did not necessarily increase the rate of learning, but the rate of forgetting was significantly reduced after trials lasting 3 months.

 To date, there have been no clinical studies that have proven acute effects of Bacopa Monnieri on human cognition. This means that there is no immediate effect from ingesting the herb however when taken consistently Bacopa’s effects become evident. This also means that there is a significantly reduced likelihood of dependency forming behavior. [7]

How Much Should I Take? Is it Safe?

The recommended dosage for Bacopa Monnieri is 300mg (at least 55% bacosides) taken daily. We include this dosage in our daily nootropic formula. Our carefully selected Bacopa is organic, vegan, non-GMO, and container 55% bacosides. Bacopa is most effective when taken as part of a nootropic or adaptogenic stack.

Adverse side effects of supplementing with Bacopa are very rarely reported. When taken the recommended dosage, the most commonly reported symptoms are nausea and gastrointestinal distress.

Bacopa Monnieri is available in our FLOW Daily Nootropic which is sold both individually and at a discount when purchased as part of our Full Stack

Questions? Feel free to email us with any questions you may have about Bacopa Monnieri or any other ingredients in our products!

References

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1. Puri HS. Rasayana; Ayruvedic Herbs for Longevity and Rejuvenation. London: Taylor and Francis, Inc.; 2003.

2. HerbalGram. 2011; American Botanical Council; Bacopa by Gayle Engels, Josef Brinckmann 

3. Pase MP. Kean J. Sarris J. Neale C. Scholey AB. Stough C. The cognitive-enhancing effects of Bacopa monnieri: A systematic review of randomized, controlled human clinical trials. J Altern Complement Med. 2012;18:1–6. [PubMed]

4. Neale C. Camfield D. Reay J. Stough C. Scholey A. Cognitive effects of two nutraceuticals Ginseng and Bacopa benchmarked against modafinil: A review and comparison of effect sizes. Br J Clin Pharmacol.2012 online publication. [PMC free article] [PubMed]

5. Stough C. Lloyd J. Clarke J. Downey LA. Hutchison CW. Rodgers T. Nathan PJ. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology. 2001;156:481–484. [PubMed]

6. Roodenrys S. Booth D. Bulzomi S. Phipps A. Micallef C. Smoker J. Chronic effects of Brahmi (Bacopa monnieri) on human memory. Neuropsychopharmacology. 2002;27:279–281. [PubMed]

7. Nathan PJ. Clarke J. Lloyd J. Hutchison CW. Downey L. Stough C. The acute effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy normal subjects. Hum Psychopharmacol.2001;16:345–351. [PubMed]

8. Aguiar S, Borowski T. Neuropharmacological Review of the Nootropic Herb Bacopa monnieri. Rejuvenation Research. 2013;16(4):313-326. doi:10.1089/rej.2013.1431. 

9. Kulkarni R. Girish KJ. Kumar A. Nootropic herbs (Medhya Rasayana) in Ayurveda: An update. Pharmacogn Rev. 2012;12:147–153. [PMC free article] [PubMed]