Proprietary Herbal Extract used in Chill

Herbs have been used traditionally and are used currently across a wide range of cultures to support health and well-being. The synergistic blend of herbs in Chill has a long history of use in Traditional Chinese Medicine (TCM). This blend has been used for supporting peace of mind and serenity in the face of everyday stressors and circumstantial stressors that individuals may experience later in life.

Rehmannia root (Rehmannia glutinosa) and Scrophularia root (Scrophularia ningpoensis) are two closely related herbs with similar supportive uses. Rehmannia is a prized herb in TCM and an extensively studied plant in modern pharmacognosy. Research studies suggest that this valuable herb supports several vital systems in the body, including the cardiovascular, immune, endocrine, and nervous systems.[1] It has been used specifically to support adrenal function, hormone balance, and a healthy journey through menopause. Chinese herbalists utilize it to nourish yin, invigorate the kidney, restore vital force, and help the body adapt to and endure physical and environmental stress.[2] Rehmannia is among a select list of herbs that have been officially approved in China for the support of blood glucose levels already within the normal range.[3] Scrophularia is present to complement the positive effects of rehmannia. According to Subhuti Dharmananda, PhD, director of the Institute for Traditional Medicine, rehmannia and scrophularia are similar in their “cold” nature and provide a number of similar benefits, including supplementation of adrenal chi.*[4]

Schisandra fruit (Schisandra chinensis) is an extensively studied adaptogen used for increasing energy and supporting the body’s natural resistance to stress. By definition, an adaptogen can decrease sensitivity to stressors while promoting stress resistance and systemic equilibrium. In vitro and animal studies suggest that schisandra has a stimulating effect on the central nervous system, enhances learning and memory, and is considered neuroprotective, hepatoprotective, cardioprotective, and gastroprotective.[5] Human studies suggest it plays an effective role in supporting physical and mental stamina.*[5]

Jujube (Zizyphus spinosa) is used in TCM for sustaining a healthy appetite, supporting healthy energy levels, and promoting a sense of inner calm.[6] Biota seed, also called oriental arborvitae seed, is combined in TCM with jujube and schisandra fruit to support a sense of tranquility, normal heart rhythm, and healthy sleep patterns.*[7]

Don Quai root (Angelica sinensis) is considered a valuable herb in TCM; it has been used for centuries to support female health and promote robust energy levels.*[8]

Chinese asparagus root (Asparagus cochinchinensis) is considered very cold in TCM. It is used to moisten dryness, nourish yin, and promote normal gastrointestinal (GI) transit time.*[9]

Ophiopogon root (Ophiopogon japonicus) is known as mai men dong in TCM. This herb, often combined with others, is used to address healthy sleep patterns, promote a sense of calm and tolerance to stress, support normal heart rhythm, and promote healthy energy levels.*[10]

Asian Ginseng root (Panax ginseng) is used as a general tonic to strengthen the body and restore vitality. It is used traditionally to support the body’s normal response to stress, maintain robust energy and alertness, support neurological health and balance, and promote healthy sleep patterns. Ginseng stimulates the pituitary to secrete adrenocorticotropic hormone (ACTH), which stimulates adrenal activity.*[11-13]

Chinese salvia root (Salvia miltiorrhiza) is a member of the Salvia genus of the Lamiaceae family. Members of the Salvia genus have been used medicinally across a variety of cultures for their relaxing effect on the central nervous system. The root of Salvia miltiorrhiza has been used specifically for support of cerebrovascular health, healthy sleep patterns, menstruation issues, and liver and kidney health.*[14]

Poria fungus (Poria wolfiporia) is a mushroom that has been used in TCM to “quiet the heart and calm the spirit” and support healthy sleep patterns.*[15]

Platycodon root (Platycodon grandiflorum) is an ancient Chinese herb associated with increased tolerance to foreign irritants, maintenance of healthy capillary permeability, and promotion of an inner sense of calm.*[16]

Grass-Leaf Sweetflag rhizome (Acorus gramineus), or Japanese sweet flag, has a long history of use in Asia for supporting health and balance in the body. Contemporary research on herbs suggest that Acorus gramineus (AG) may play a role in supporting neuronal health and memory.[17] Animal studies suggest that the asarone essential oil in AG has a specific, neuroprotective effect.*[18]

Scientific Research and Evidence 

1. Zhang RX, Li MX, Jia ZP. Rehmannia glutinosa: review of botany, chemistry and pharmacology. J Ethnopharmacol. 2008 May 8;117(2):199-214. Review. [PMID: 18407446]

2. Huang CH. The Pharmacology of Chinese Herbs. 2nd ed. New York, NY: CRC Press; 1999:264-65.

3. Jia W, Gao W, Tang L. Antidiabetic herbal drugs officially approved in China. Phytother Res. 2003 Dec;17(10):1127-34. Review. [PMID: 14669243]

4. Dharmananda S. Rehmannia. March 1999. rehmann.htm. Accessed March 25, 2013.

5. Panossian A, Wikman G. Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress-protective activity. Review. Pharmaceuticals. 2010;3(1):188-224. doi:10.3390/ph3010188.

6. Chen J, Chen T. Suan Zoa Ren. Chinese Medical Herbology and Pharmacology. City of Industry, CA: Art of Medicine Press; 2004:762.

7. Cheng R. Semen Biotae.TCM Basics website. materiamedica/semen_biotae.htm. Accessed March 28, 2013.

8. Krinsky DL, LaValle JB, Hawkins EB, et al. Natural Therapeutics Pocket Guide. 2nd ed. Hudson, OH: Lexi-Comp; 2003:426-7.

9. Chen J, Chen, T. Tian Men Dong. Chinese Medical Herbology and Pharmacology. City of Industry, CA: Art of Medicine Press; 2004:946.

10. Chen J, Chen, T. Tian Men Dong. Chinese Medical Herbology and Pharmacology. City of Industry, CA: Art of Medicine Press; 2004:943-5.

11. Chen J, Chen, T. Ren Shen. Chinese Medical Herbology and Pharmacology. City of Industry, CA: Art of Medicine Press; 2004:835-40.

12. Natural Standard Database. Ginseng. databases/herbssupplements/ginseng.asp?#undefined. Accessed March 26, 2013.

13. Natural Medicines Comprehensive Database. Ginseng, Panax. MedlinePlus. Updated December 11, 2012. Accessed March 26, 2013.

14. Imanshahidi M, Hosseinzadeh H. The pharmacological effects of Salvia species on the central nervous system. Phytother Res. 2006 Jun;20(6):427-37. Review. [PMID: 16619340]

15. Poria – Wolfiporia extensa. Ottawa, Ontario: Health Canada: 2012. http:// Accessed March 28, 2013.

16. Chen J, Chen T. Jie Geng. Chinese Medical Herbology and Pharmacology. City of Industry, CA: Art of Medicine Press; 2004:696-7.

17. Jesky R, Hailong C. Are herbal compounds the next frontier for alleviating learning and memory impairments? An integrative look at memory, dementia and the promising therapeutics of traditional Chinese medicines. Phytother Res. 2011 Aug;25(8):1105-18. Review. [PMID: 21305632]

18. Cho J, Kim YH, Kong JY, et al. Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus. Life Sci. 2002 Jun 21;71(5):591-9. [PMID: 12052443]